Pub. Date : 2018 Sep
PMID : 30064964
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We recently developed a BBB-penetrating IDS fusion protein, JR-141, and demonstrated its ability to reduce GAG accumulation in the brain of human transferrin receptor knock-in and Ids knock-out mice (TFRC-KI/Ids-KO), an animal model of MPS II, following intravenous administration. | Glycosaminoglycans | iduronate 2-sulfatase | Homo sapiens |