Pub. Date : 2018 Jul 24
PMID : 30041644
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the present study, we studied the expression of Foxo1, Gsk3beta and PI3K-Akt-mTOR in the brain of streptozotocin-induced type 2 diabetes mellitus Wistar rats. | Streptozocin | forkhead box O1 | Rattus norvegicus |
2 | Brain tissue of STZ-induced type 2 DM animals showed a significant reduction in secondary messengers of insulin signalling (Foxo1) (P < 0.001) and Gsk3beta (P < 0.01) and a significant alteration in the expression of phosphorylated-Akt (P < 0.001) mTOR (P < 0.01) and PI3K. | Streptozocin | forkhead box O1 | Rattus norvegicus |