Pub. Date : 2018 Aug 5
PMID : 30025348
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this work we describe neurogenic and neuroprotective donepezil-flavonoid hybrids (DFHs), exhibiting nanomolar affinities for the sigma-1 receptor (sigma1R) and inhibition of key enzymes in Alzheimer"s disease (AD), such as acetylcholinesterase (AChE), 5-lipoxygenase (5-LOX), and monoamine oxidases (MAOs). | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | In this work we describe neurogenic and neuroprotective donepezil-flavonoid hybrids (DFHs), exhibiting nanomolar affinities for the sigma-1 receptor (sigma1R) and inhibition of key enzymes in Alzheimer"s disease (AD), such as acetylcholinesterase (AChE), 5-lipoxygenase (5-LOX), and monoamine oxidases (MAOs). | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |