Title : Aspirin Suppresses PGE2 and Activates AMP Kinase to Inhibit Melanoma Cell Motility, Pigmentation, and Selective Tumor Growth In Vivo.

Pub. Date : 2018 Oct

PMID : 30021726






1 Functional Relationships(s)
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1 ASA and the COX-2 inhibitor celecoxib did not affect melanoma cell viability, but significantly reduced colony formation, cell motility, and pigmentation (melanin production) in vitro at concentrations of 1 mmol/L and 20 mumol/L, respectively. Celecoxib cytochrome c oxidase II, mitochondrial Mus musculus