Title : Low dosage of arsenic trioxide (As2O3) inhibits angiogenesis in epithelial ovarian cancer without cell apoptosis.

Pub. Date : 2018 Aug

PMID : 30014256






5 Functional Relationships(s)
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1 In addition, As2O3-treated epithelial ovarian cancer cells show a decreased VEGFA, VEGFR2 and CD31 mRNA expression. Arsenic Trioxide vascular endothelial growth factor A Homo sapiens
2 As per the underlying mechanisms involved in As2O3 treatment, we found that As2O3 inhibits VEGFA and VEGFR2 expression that thereby inhibits the VEGFA-VEGFR2-PI3K/ERK signaling pathway. Arsenic Trioxide vascular endothelial growth factor A Homo sapiens
3 As per the underlying mechanisms involved in As2O3 treatment, we found that As2O3 inhibits VEGFA and VEGFR2 expression that thereby inhibits the VEGFA-VEGFR2-PI3K/ERK signaling pathway. Arsenic Trioxide vascular endothelial growth factor A Homo sapiens
4 As per the underlying mechanisms involved in As2O3 treatment, we found that As2O3 inhibits VEGFA and VEGFR2 expression that thereby inhibits the VEGFA-VEGFR2-PI3K/ERK signaling pathway. Arsenic Trioxide vascular endothelial growth factor A Homo sapiens
5 As per the underlying mechanisms involved in As2O3 treatment, we found that As2O3 inhibits VEGFA and VEGFR2 expression that thereby inhibits the VEGFA-VEGFR2-PI3K/ERK signaling pathway. Arsenic Trioxide vascular endothelial growth factor A Homo sapiens