Title : TP53 mutations predict for poor survival in ALK rearrangement lung adenocarcinoma patients treated with crizotinib.

Pub. Date : 2018 May

PMID : 29997966






3 Functional Relationships(s)
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1 TP53 mutations predict for poor survival in ALK rearrangement lung adenocarcinoma patients treated with crizotinib. Crizotinib tumor protein p53 Homo sapiens
2 We analyze the impact of TP53 mutations on response to crizotinib in patients with ALK rearrangement NSCLC. Crizotinib tumor protein p53 Homo sapiens
3 Conclusions: TP53 mutations reduce responsiveness to crizotinib and worsen prognosis in ALK rearrangement NSCLC patients. Crizotinib tumor protein p53 Homo sapiens