Title : CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function.

Pub. Date : 2018 Jul 24

PMID : 29997173






1 Functional Relationships(s)
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Protein Name
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1 CD52-Fc bound specifically to the proinflammatory Box B domain of HMGB1, and this in turn promoted binding of the CD52 N-linked glycan, in alpha-2,3 sialic acid linkage with galactose, to Siglec-10. n-linked glycan sialic acid binding Ig like lectin 10 Homo sapiens