Title : The affinity of (-)-propranolol for beta 1- and beta 2-adrenoceptors of human heart. Differential antagonism of the positive inotropic effects and adenylate cyclase stimulation by (-)-noradrenaline and (-)-adrenaline.

Pub. Date : 1985 Oct

PMID : 2999616






1 Functional Relationships(s)
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1 (-)-Propranolol antagonized the effects of (-)-noradrenaline mediated by beta 2-adrenoceptors 2 to 3 times more potently than the effects mediated by beta 1-adrenoceptors. Norepinephrine potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens