Pub. Date : 2018 Oct
PMID : 29981383
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hydroxychloroquine efficiently suppresses inflammatory responses of human class-switched memory B cells via Toll-like receptor 9 inhibition. | Hydroxychloroquine | toll like receptor 9 | Homo sapiens |
2 | Hydroxychloroquine efficiently inhibited the mammalian target of rapamycin complex 1, differentiation of CD19+IgD-CD27+ class-switched memory B cells to plasmablasts and their IgG production, under stimulation with CpG, a Toll-like receptor (TLR)-9 ligand. | Hydroxychloroquine | toll like receptor 9 | Homo sapiens |
3 | Taken together, hydroxychloroquine markedly suppresses the TLR9-mediated human B cell functions during inflammatory processes. | Hydroxychloroquine | toll like receptor 9 | Homo sapiens |