Pub. Date : 2018 Aug 3
PMID : 29980590
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Depletion of PI4KIIIalpha results in impaired electrical responses to light, and reduced plasma membrane levels of PI4P and PI(4,5)P2 Depletion of the conserved proteins Efr3 and TTC7 [also known as StmA and L(2)k14710, respectively, in flies], which assemble PI4KIIIalpha at the plasma membrane, also results in an impaired light response and reduced plasma membrane PI4P and PI(4,5)P2 levels. | pi(4,5)p2 | Phosphatidylinositol 4-kinase III alpha | Drosophila melanogaster |
| 2 | Depletion of PI4KIIIalpha results in impaired electrical responses to light, and reduced plasma membrane levels of PI4P and PI(4,5)P2 Depletion of the conserved proteins Efr3 and TTC7 [also known as StmA and L(2)k14710, respectively, in flies], which assemble PI4KIIIalpha at the plasma membrane, also results in an impaired light response and reduced plasma membrane PI4P and PI(4,5)P2 levels. | pi(4,5)p2 | Phosphatidylinositol 4-kinase III alpha | Drosophila melanogaster |
| 3 | Thus, PI4KIIIalpha activity at the plasma membrane generates PI4P and supports PI(4,5)P2 levels during receptor activated PLC signaling. | pi(4,5)p2 | Phosphatidylinositol 4-kinase III alpha | Drosophila melanogaster |