Title : [Change of hepatic drug metabolism enzymes in rat depression model with kidney-yang deficiency].

Pub. Date : 2017 Feb

PMID : 29979512






1 Functional Relationships(s)
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1 Tolbutamide, chlorzoxazone, theophylline, midazolam, omeprazole and dextromethorphanwere used as substrates of CYP2C6, CYP2E1, CYP1A2, CYP3A2, CYP2D1, and CYP2D2 to test the depressionimpact on drug metabolism. Midazolam cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus