Pub. Date : 2018 Aug
PMID : 29968502
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BDNF levels were analyzed in the hippocampus of animals treated with cannabidiol (10 mg/kg). | Cannabidiol | brain derived neurotrophic factor | Mus musculus |
| 2 | RESULTS: Systemic cannabidiol administration induced antidepressant-like effects and increased BDNF levels in the dorsal hippocampus. | Cannabidiol | brain derived neurotrophic factor | Mus musculus |
| 3 | CONCLUSION: Altogether, our data suggest that the hippocampal BDNF-TrkB-mTOR pathway is vital for cannabidiol-induced antidepressant-like effect when the drug is locally administered. | Cannabidiol | brain derived neurotrophic factor | Mus musculus |