Title : Rac1 Nanoscale Organization on the Plasma Membrane Is Driven by Lipid Binding Specificity Encoded in the Membrane Anchor.

Pub. Date : 2018 Sep 15

PMID : 29967243






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Rac1 also selectively interacts with phosphatidic acid (PA) and phosphoinositol (3,4,5)-trisphosphate (PIP3), resulting in nanoclusters enriched in these lipids. PIP3 Rac family small GTPase 1 Homo sapiens
2 These lipids are structurally important because depleting the PM of PA or PIP3 impairs both Rac1 PM binding and Rac1 nanoclustering. PIP3 Rac family small GTPase 1 Homo sapiens
3 These lipids are structurally important because depleting the PM of PA or PIP3 impairs both Rac1 PM binding and Rac1 nanoclustering. PIP3 Rac family small GTPase 1 Homo sapiens