Pub. Date : 2018 Jun 12
PMID : 29963241
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Compared to CPT-11, L-OHP is a stronger inducer of caspases and p53-dependent apoptosis. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 2 | We additionally show that L-OHP suppresses survivin through p53 and its downstream target p21, which stalls cell cycle progression as a cyclin-dependent kinase inhibitor (CDKi). | Oxaliplatin | tumor protein p53 | Homo sapiens |