Title : The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice.

Pub. Date : 2018 Jul

PMID : 29936316






1 Functional Relationships(s)
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1 We found that both aggregation and polyQ-induced reactive oxygen species can be significantly prohibited by the tested NC009 compounds in Tet-On TBP/Q79 293 cells. polyglutamine TATA-box binding protein Homo sapiens