Title : COX-2 inhibition by celecoxib in epithelial ovarian cancer attenuates E-cadherin suppression through reduced Snail nuclear translocation.

Pub. Date : 2018 Aug 25

PMID : 29932878






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 COX-2 inhibition by celecoxib in epithelial ovarian cancer attenuates E-cadherin suppression through reduced Snail nuclear translocation. Celecoxib snail family transcriptional repressor 1 Homo sapiens
2 Depletion of COX-2, by celecoxib treatment, resulted in attenuated nuclear translocation of Snail, and, in turn, significantly increased E-cadherin in EOC cell line SKOV3, which was established to be due to the reduced binding of Snail onto E-cadherin promoter. Celecoxib snail family transcriptional repressor 1 Homo sapiens