Title : Vitamin D3 Modulates Impaired Crosstalk Between RANK and Glucocorticoid Receptor Signaling in Bone Marrow Cells After Chronic Prednisolone Administration.

Pub. Date : 2018

PMID : 29930537






2 Functional Relationships(s)
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1 Cholecalciferol prevented prednisolone-elicited disturbances of the RANKL/RANK/OPG, which correlated with improved bioavailability and vitamin D signaling through VDR. Cholecalciferol TNF superfamily member 11 Rattus norvegicus
2 Our findings suggest that prednisolone-induced abnormalities in GR and RANKL/RANK/OPG signaling pathways are associated with the impairments of vitamin D auto/paracrine system in BM cells and can be ameliorated by cholecalciferol supplementation. Cholecalciferol TNF superfamily member 11 Rattus norvegicus