Title : The coordinated effects of Apatinib and Tripterine on the proliferation, invasiveness and apoptosis of human hepatoma Hep3B cells.

Pub. Date : 2018 Jul

PMID : 29928421






2 Functional Relationships(s)
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1 The downregulation of p-Akt and p-ERK induced by Apatinib and Tripterine was further inhibited in the combination group (P<0.05), and the expression levels of Caspase-3 and Bax were also significantly increased in the combination group (P<0.05). celastrol BCL2 associated X, apoptosis regulator Homo sapiens
2 The combination of Apatinib and Tripterine significantly inhibited the proliferation, migration and invasion ability and promoted the apoptosis of Hep3B cells by downregulating the expression of p-Akt and p-ERK, and upregulating the expression of Caspase-3 and Bax. celastrol BCL2 associated X, apoptosis regulator Homo sapiens