Title : Tumor necrosis factor receptor 2 may promote the proliferation and drug resistance of Kapras299 and L428 lymphoma cells via the AKT and WNT/β-catenin signaling pathways.

Pub. Date : 2018 Jun

PMID : 29928327






2 Functional Relationships(s)
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1 In L428 cells overexpressing TNFR2, the beta-catenin blocker, DKK1, or the AKT inhibitor, LY294002, abrogated the increase in proliferation induced by TNFR2 and increased cell inhibition rate upon treatment with ADM. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one TNF receptor superfamily member 1B Homo sapiens
2 In L428 cells overexpressing TNFR2, the beta-catenin blocker, DKK1, or the AKT inhibitor, LY294002, abrogated the increase in proliferation induced by TNFR2 and increased cell inhibition rate upon treatment with ADM. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one TNF receptor superfamily member 1B Homo sapiens