Pub. Date : 2018
PMID : 29922176
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TRPV1 activation by high doses of CAP (>10 muM) leads to necrosis, but also exhibits apoptotic characteristics. | Capsaicin | latexin | Homo sapiens |
| 2 | Low concentrations of CAP (1 muM) induce cell death by a mechanism involving a TRPV1-mediated rapid and transient intracellular Ca2+ increase that stimulates plasma membrane depolarization, thereby compromising plasma membrane integrity and ultimately leading to cell death. | Capsaicin | latexin | Homo sapiens |