Pub. Date : 1985 Jun
PMID : 2992067
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The preparation of 125I-labelled gastrin 1-17, using Iodo-gen as oxidizing agent, is described. | 1,3,4,6-tetrachloro-3 alpha,6 alpha-diphenylglycoluril | gastrin | Rattus norvegicus |
| 2 | The Iodo-gen-labelled 125I-gastrin tracer showed a slightly higher immunoreactivity than a similarly purified tracer produced by a gentle chloramine-T method (50% binding of 0.45 fmol tracer at an antibody dilution of 945,000 versus 780,000, respectively). | 1,3,4,6-tetrachloro-3 alpha,6 alpha-diphenylglycoluril | gastrin | Rattus norvegicus |
| 3 | The Iodo-gen-labelled 125I-gastrin, which had the same biological activity as native gastrin when tested in conscious gastric fistula rats, was tested for specific binding at 30 degrees C in pronase-isolated rat gastric fundic cells and plasma membranes from the same area. | 1,3,4,6-tetrachloro-3 alpha,6 alpha-diphenylglycoluril | gastrin | Rattus norvegicus |
| 4 | This study shows that Iodo-gen is suitable as an oxidizing agent in iodination of gastrin without loss of biological activity. | 1,3,4,6-tetrachloro-3 alpha,6 alpha-diphenylglycoluril | gastrin | Rattus norvegicus |