Title : Application of kinomic array analysis to screen for altered kinases in atrial fibrillation remodeling.

Pub. Date : 2018 Nov

PMID : 29902583






1 Functional Relationships(s)
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1 RESULTS: While tachypacing changed activity of 50 kinases, 40 of these were prevented by geranylgeranylacetone and involved in differentiation and proliferation (SRC), contraction, metabolism, immunity, development, cell cycle (CDK4), and survival (Akt). geranylgeranylacetone SRC proto-oncogene, non-receptor tyrosine kinase Canis lupus familiaris