Title : Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate‑induced apoptosis.

Pub. Date : 2018 Sep

PMID : 29901098






1 Functional Relationships(s)
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1 Notably, pharmacological blockade of autophagy activation using hydroxychloroquine markedly enhanced ART-induced apoptosis and increased the protein levels of cleaved caspase 3 and PARP, while decreasing the levels of LC3 and beclin-1. Hydroxychloroquine microtubule associated protein 1 light chain 3 alpha Homo sapiens