Pub. Date : 2018 May 25
PMID : 29899840
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CD44 was significantly increased in Huh7 cells made resistant to sorafenib. | Sorafenib | CD44 molecule (Indian blood group) | Homo sapiens |
| 2 | Moreover, a combination of INK128 and sorafenib showed improved anti-proliferative effects in CD44high HCC cells. | Sorafenib | CD44 molecule (Indian blood group) | Homo sapiens |
| 3 | Since the clinical response to sorafenib is highly variable, our findings suggest that ATP-competitive mTOR inhibitors may be effective in treating advanced, CD44-expressing HCC patients who are insensitive to sorafenib. | Sorafenib | CD44 molecule (Indian blood group) | Homo sapiens |