Title : Organocatalytic Asymmetric Reduction of Fluorinated Alkynyl Ketimines.

Pub. Date : 2018 Aug 3

PMID : 29884023






1 Functional Relationships(s)
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1 In addition, iodocyclization of fluorinated propargylamine affords chiral 3-iodo-2-(trifluoromethyl)-1,2-dihydroquinoline, which can be easily converted to 2-(trifluoromethyl)- 1,2-dihydroquinoline derivatives with the selective COX-2 inhibitory activity. propargylamine mitochondrially encoded cytochrome c oxidase II Homo sapiens