Title : Icariin, but Not Genistein, Exerts Osteogenic and Anti-apoptotic Effects in Osteoblastic Cells by Selective Activation of Non-genomic ERĪ± Signaling.

Pub. Date : 2018

PMID : 29867480






1 Functional Relationships(s)
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1 Confocal imaging studies confirmed that the phosphorylation of ERalpha at Ser 118 and Ser 167 by genistein and icariin in MC3T3-E1 cells was mediated via MAPK- and PI3K-dependent pathway, respectively. Genistein estrogen receptor 1 (alpha) Mus musculus