Title : Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Rα mutations.

Pub. Date : 2018 Apr 27

PMID : 29854301






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Venetoclax, an inhibitor of BCL-2, showed activity against the transformed cell line in vitro and could be combined with ruxolitinib in vivo. venetoclax B cell leukemia/lymphoma 2 Mus musculus