Title : MPA-modified CdTe quantum dots increased interleukin-1beta secretion through MyD88-dependent Toll-like receptor pathway and NLRP3 inflammasome activation in microglia.

Pub. Date : 2018 Oct

PMID : 29852215






2 Functional Relationships(s)
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1 Molecular biology analyses suggested that both TLR2/MyD88/NF-kappaB pathway and NLRP3 inflammasome participated in the CdTe QD-induced IL-1ss secretion. cadmium telluride interleukin 1 complex Mus musculus
2 The results, taken together, demonstrated that MPA-modified CdTe QDs exposure with a high concentration was capable of activating microglial cells and promoting IL-1ss secretion, which was highly correlated with the activations of both TLR2/MyD88/NF-kappaB pathway and ROS-induced NLRP3 inflammasome. cadmium telluride interleukin 1 complex Mus musculus