Title : Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective.

Pub. Date : 2018 Oct 25

PMID : 29847930






1 Functional Relationships(s)
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Protein Name
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1 Isocitrate dehydrogenases 1 and 2 (IDH1/2) are homodimeric enzymes that catalyze the conversion of isocitrate to alpha-ketoglutarate (alpha-KG) in the tricarboxylic acid cycle. Tricarboxylic Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens