Title : TNF-alpha and TNF-R1 regulate bupivacaine-induced apoptosis in spinal cord dorsal root ganglion neuron.

Pub. Date : 2018 Aug 15

PMID : 29802833






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1 In addition, qRT-PCR and western blot demonstrated that downstream substrates of apoptotic and TNF signaling pathways, caspase-9, MAP3K and JNK, were all significantly downregulated by TNF-alpha or TNF-R1 inhibition, but not by TNF-R2 inhibition, in bupivacaine-injured DRG. Bupivacaine caspase 9 Mus musculus