Pub. Date : 2018 May 25
PMID : 29802399
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with OCA effectively prevented chronic inflammation and liver fibrosis in WD-fed MC4R-KO mice with only marginal effect on body weight and hepatic steatosis. | obeticholic acid | melanocortin 4 receptor | Mus musculus |
| 2 | Intriguingly, treatment with OCA markedly reduced hCLS formation even after MC4R-KO mice developed NASH, thereby inhibiting the progression of liver fibrosis. | obeticholic acid | melanocortin 4 receptor | Mus musculus |