Title : The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior.

Pub. Date : 2018 May 24

PMID : 29795045






1 Functional Relationships(s)
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1 Our structural studies show that in hCA VII the network of ordered water molecules, which connects the zinc bound solvent molecule to the proton shuttle His64, is altered compared to hCA II, causing a reduction of the catalytic efficiency. Water carbonic anhydrase 2 Homo sapiens