Pub. Date : 2018 Sep
PMID : 29794149
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using the direct NLRP3 inhibitor, CY-09, we demonstrated significantly reduced human platelet aggregation in response to threshold concentrations of collagen and ADP, as well as impaired clot retraction in CY-09-treated human platelets, supporting a role for NLRP3 also in regulating human platelet alphaIIbbeta3 outside-in signaling. | CY5.5 cyanine dye | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Using the direct NLRP3 inhibitor, CY-09, we demonstrated significantly reduced human platelet aggregation in response to threshold concentrations of collagen and ADP, as well as impaired clot retraction in CY-09-treated human platelets, supporting a role for NLRP3 also in regulating human platelet alphaIIbbeta3 outside-in signaling. | CY5.5 cyanine dye | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Using the direct NLRP3 inhibitor, CY-09, we demonstrated significantly reduced human platelet aggregation in response to threshold concentrations of collagen and ADP, as well as impaired clot retraction in CY-09-treated human platelets, supporting a role for NLRP3 also in regulating human platelet alphaIIbbeta3 outside-in signaling. | CY5.5 cyanine dye | NLR family pyrin domain containing 3 | Homo sapiens |