Title : Development of Novel Therapeutics Targeting Isocitrate Dehydrogenase Mutations in Cancer.

Pub. Date : 2018

PMID : 29773061






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) are key metabolic enzymes that catalyze the conversion of isocitrate to alpha-ketoglutarate (alphaKG). Ketoglutaric Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens