Title : Modulating Chemosensitivity of Tumors to Platinum-Based Antitumor Drugs by Transcriptional Regulation of Copper Homeostasis.

Pub. Date : 2018 May 16

PMID : 29772714






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Drug importing, intracellular shuffling, and exporting-carried out by the high-affinity copper (Cu) transporter (hCtr1), Cu chaperone (Ato x1), and Cu exporters (ATP7A and ATP7B), respectively-cumulatively contribute to the chemosensitivity of Pt drugs including cisplatin and carboplatin, but not oxaliplatin. Cisplatin solute carrier family 31 member 1 Homo sapiens