Title : A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice.

Pub. Date : 2018 Aug 15

PMID : 29771357






3 Functional Relationships(s)
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1 A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice. halofuginone synaptotagmin VII Mus musculus
2 While halofuginone did not affect patch-repair-complex key proteins, it further enhanced Syt-7 levels and its spread across the cytosol in dysf-/- myofibers and muscle tissue, and increased its co-localization with lysosomes. halofuginone synaptotagmin VII Mus musculus
3 Together, the data imply a novel role for halofuginone in membrane-resealing events with Syt-7 possibly taking part in these events. halofuginone synaptotagmin VII Mus musculus