Title : Chemopreventive activity of celastrol in drug-resistant human colon carcinoma cell cultures.

Pub. Date : 2018 Apr 20

PMID : 29765532






1 Functional Relationships(s)
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1 With the use of flow cytometry we have shown that celastrol reduces the cell size of the SP (side population; subpopulation of cancer cells enriched with cancer stem cells), increases frequency of apoptosis and binds to Pgp protein in cell membranes inhibiting its transport function. celastrol phosphoglycolate phosphatase Homo sapiens