Title : Rational Discovery of Novel Squalene Synthase Inhibitors through Pharmacophore Modelling.

Pub. Date : 2018

PMID : 29732977






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 INTRODUCTION: In the present research work, a pharmacophore based virtual screening was performed using Discovery Studio 2.1 for the discovery of some novel molecules as inhibitors of Squalene Synthase Enzyme, a key enzyme in cholesterol biosynthetic pathway. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens