Title : Sequential Treatment Escalation with Dapagliflozin and Saxagliptin Improves Beta Cell Function in Type 2 Diabetic Patients on Previous Metformin Treatment: An Exploratory Mechanistic Study.

Pub. Date : 2018 May

PMID : 29727906






2 Functional Relationships(s)
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Protein Name
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1 Treatment with dapagliflozin reduced fasting glucose levels and insulin resistance (TP1). dapagliflozin transition protein 1 Homo sapiens
2 Within the hyperglycaemic clamp, C-peptide and insulin concentrations increased after the addition of dapagliflozin in TP1 (0.48+-0.45 nmol*h/l; 6.24+-17.9 mU*h/l) and further improved after the addition of saxagliptin in TP2 (0.38+-0.34 nmol*h/l; 6.59+-10.15 mU*h/l). dapagliflozin transition protein 1 Homo sapiens