Title : The SHH/Gli axis regulates CD90-mediated liver cancer stem cell function by activating the IL6/JAK2 pathway.

Pub. Date : 2018 Jul

PMID : 29722127






1 Functional Relationships(s)
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1 Application of the JAK2 inhibitor AZD1480 and IL6 neutralizing antibody showed the CD90 and SHH/Gli-regulated liver cancer stem cell functions were mediated by the IL6/JAK2/STAT3 pathway. AZD 1480 sonic hedgehog signaling molecule Homo sapiens