Pub. Date : 2018
PMID : 29721066
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rational: In a subset of cancers, arginine auxotrophy occurs due to the loss of expression of argininosuccinate synthetase 1 (ASS1). | Arginine | argininosuccinate synthase 1 | Homo sapiens |
| 2 | Rational: In a subset of cancers, arginine auxotrophy occurs due to the loss of expression of argininosuccinate synthetase 1 (ASS1). | Arginine | argininosuccinate synthase 1 | Homo sapiens |
| 3 | This loss of ASS1 expression makes cancers sensitive to arginine starvation that is induced by PEGylated arginine deiminase (ADI-PEG20). | Arginine | argininosuccinate synthase 1 | Homo sapiens |