Title : Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer.

Pub. Date : 2018 Apr 6

PMID : 29719602






1 Functional Relationships(s)
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1 In addition, leptin reduced the 5-FU effects on apoptosis by decreasing pro-apoptotic (Bax, Caspase-3 activation and PARP degradation) and increasing anti-apoptotic factors (RIP and Bcl-XL). Fluorouracil BCL2 like 1 Homo sapiens