Title : MDM2 controls NRF2 antioxidant activity in prevention of diabetic kidney disease.

Pub. Date : 2018 Aug

PMID : 29704532






1 Functional Relationships(s)
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1 On the contrary, P53 inhibition by pifithrin-alpha activated renal NRF2 signaling and the expression of Mdm2, and attenuated DKD in the WT diabetic mice, but not in the Nrf2 KO diabetic mice. pifithrin nuclear factor, erythroid derived 2, like 2 Mus musculus