Title : Extensive Gene Amplification as a Mechanism for Piperacillin-Tazobactam Resistance in Escherichia coli.

Pub. Date : 2018 Apr 24

PMID : 29691340






1 Functional Relationships(s)
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1 Although the TEM-1 beta-lactamase (BlaTEM-1) hydrolyzes penicillins and narrow-spectrum cephalosporins, organisms expressing this enzyme are typically susceptible to beta-lactam/beta-lactamase inhibitor combinations such as piperacillin-tazobactam (TZP). Cephalosporins TEM-1 beta-lactamase Escherichia coli