Title : Fibroblast Growth Factor 15-Dependent and Bile Acid-Independent Promotion of Liver Regeneration in Mice.

Pub. Date : 2018 Nov

PMID : 29672888






2 Functional Relationships(s)
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1 The mechanisms by which Fgf15 promotes liver regeneration are unclear, but Fgf15 may do so indirectly by reducing BA levels and/or directly by promoting cell proliferation. Bile Acids and Salts fibroblast growth factor 15 Mus musculus
2 In this study, we aimed to clarify these relationships by generating Fgf15 Tet-Off, transgenic mice (Fgf15 Tg) that had very low BA levels as a result from overexpressed Fgf15-mediated suppression of BA synthesis. Bile Acids and Salts fibroblast growth factor 15 Mus musculus