Title : APR-246 reactivates mutant p53 by targeting cysteines 124 and 277.

Pub. Date : 2018 May 1

PMID : 29670092






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 APR-246 is converted to the reactive electrophile methylene quinuclidinone (MQ), which binds covalently to p53 core domain. SCHEMBL4738034 tumor protein p53 Homo sapiens