Title : AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus.

Pub. Date : 2018 Apr 12

PMID : 29650969






1 Functional Relationships(s)
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1 Congenital NDI is mainly caused by loss-of-function mutations in the vasopressin type 2 receptor (V2R), leading to impaired aquaporin-2 (AQP2) water channel activity. Water arginine vasopressin receptor 2 Homo sapiens