Title : Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.

Pub. Date : 2018 Jun 15

PMID : 29635516






1 Functional Relationships(s)
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1 Treatment of Tsc2+/- mice with the ornithine decarboxylase inhibitor alpha-difluoromethylornithine, to reduce putrescine synthesis dose-dependently reduced hippocampal astrogliosis. Eflornithine ornithine decarboxylase, structural 1 Mus musculus