Title : Association between mutant IDHs and tumorigenesis in gliomas.

Pub. Date : 2018 Dec

PMID : 29633022






1 Functional Relationships(s)
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1 Moreover, mutant IDH1 can drive the immortalization and transformation of p53-/pRb-deficient astrocytes by reactivating telomerase and stabilizing telomeres in combination with increased histone lysine methylation and c-Myc/Max binding at the TERT promoter. Lysine tumor protein p53 Homo sapiens