Title : Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death.

Pub. Date : 2018 May 15

PMID : 29626488






2 Functional Relationships(s)
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1 Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death. Berberine AKT serine/threonine kinase 1 Homo sapiens
2 Thus, our findings suggest that PHLPP2, Akt and Mst1 constitute an autoinhibitory triangle which may be partly responsible for antiproliferative effect of berberine. Berberine AKT serine/threonine kinase 1 Homo sapiens